Normal transferrin saturation level in the blood. Copyright © Health Hearty & Buzzle.com, Inc. Nutritional supplements must always be taken under medical supervision, so consult a doctor regarding the dosage of iron supplements. If iron absorption is abnormally high, transferrin gets saturated with iron. Necessary cookies are absolutely essential for the website to function properly. Iron Disorders Institute. If the blood tests reveal low levels of iron in blood, one must follow a healthy diet in order to restore the TSAT levels to normal. Thus, intestinal disorders must be treated at the earliest. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. To learn more about these tests visit tests to determine iron levels. Since iron is required for several vital bodily processes, an iron deficiency or overload is bound to have serious repercussions on one’s health. Iron is one of the most essential nutrients that is required for the healthy functioning of the human body. Individuals who may have iron poisoning will generally have high iron saturation percentages and an overall high iron count, but will have normal ferritin and TIBC levels with low UIBC results. Serum iron, TIBC and ferritin tests are usually performed together.
Iron deficiency without anemia can occur when a person has a normal hemoglobin, but below normal serum ferritin and/or transferrin saturation. Total iron and ferritin blood tests will also be high. This is why some medical providers may recommend an iron saturation blood test as part of an annual medical exam. Hemolytic Anemia: This condition is represented by a high saturation percentage and a high iron and ferritin count.
Clinical chemistry and laboratory medicine: CCLM / FESCC. Low transferrin saturation level in the blood.
What is iron deficiency? Iron deficiency can also be caused by certain medications, some dietary supplements or substances that cause bleeding such as pain relievers with aspirin, and also as a result of poisoning from lead, toxic chemicals or alcohol abuse. A diagnosis of iron deficiency can be made when a person has both low hemoglobin and hematocrit and low serum ferritin. ), The Secret Science of Solving Crossword Puzzles, Racist Phrases to Remove From Your Mental Lexicon. Individuals who suffer from Crohn's disease find that the walls of their intestines become thickened and damaged, making it difficult for iron to absorb through the small intestine's wall. Intestinal disorders could affect the process of iron absorption thereby lowering the TSAT levels. When there is a lack of high-iron foods in the diet, such as red meat, liver, or egg yolks, then without supplementation, there is the potential for a deficiency to be present. Most people, however, have no initial symptoms when iron levels are at an inappropriate level. On the other hand, TSAT percentage will be low if iron absorption is low.
Iron is a key component of hemoglobin, which is a protein that helps in transporting oxygen throughout our body. What does a normal blood transferrin saturation percentage mean? - Low serum iron cannot be interpreted in isolation because it might be seen in infection, inflammation, and malignancy as well as iron deficiency.5 We recommend measuring C reactive protein if serum ferritin is normal or high with serum iron or transferrin saturation below their …
What does a high blood transferrin saturation percentage mean? Iron is an essential nutrient which is why there’s a great need to include sources of iron in one’s diet in the required quantity. Is the Coronavirus Crisis Increasing America's Drug Overdoses? World journal of pediatrics : WJP. Diseased states that reduce the presence of iron in the body include extensive cancer, uremia, nephrotic syndrome and tissue inflammation states. While serum iron test measures the amount of circulating iron that is bound to a blood plasma glycoprotein called transferrin, ferritin test measures the levels of ferritin. What is low transferrin saturation percentage called? Under normal circumstances, serum iron must lie between 60 to 170 μg/dl, whereas reference range for TIBC is 240-450 μg/dl. Links to more information about iron deficiency: US Centers for Disease Control and Prevention MMWR (CDC Morbidity and Mortality Weekly Report, https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5140a1.htm, US Centers for Disease Control and Prevention Division of Nutrition, https://www.cdc.gov/nutrition/index.html https://www.cdc.gov/nutrition/micronutrient-malnutrition/index.html https://www.cdc.gov/nutrition/micronutrient-malnutrition/micronutrients/index.html https://www.cdc.gov/nccdphp/dnpao/index.html, The Agency for Healthcare and Research Quality (AHRQ), Gerry Koenig - The Dangers of Misdiagnosis. In the same way high iron content than what is required in the body is also detrimental to health. There will be frequent spells of feeling tired, but not exhausted, and some may have a skin color that is more pale than normal. If you suspect an iron deficiency, before having a blood test ordered, it is important to speak with your doctor about any chronic pain, infections, or inflammation that are present. Since excessive consumption of foods that are rich in calcium can inhibit iron absorption, it would be a good idea to cut down on your intake of dairy products or calcium supplements. Iron deficiency is a condition resulting from too little iron in the body. If this test comes back as normal, along with other iron tests, then another cause for the anemia will need to be found. This person is usually unable to absorb iron, regardless of how much he eats. “Iron deficiency is a medical condition that leads to anemia.” Deepa Sekhar, M.D., MSc. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. There are some circumstances than can reduce your transferrin saturation: Lower than normal transferrin saturation can be due to: The following values are considered to be below the normal range: IMPORTANT: These levels are expressed in %. Iron deficiency can result in poor memory or poor cognitive skills (mental function) and can result in poor performance in school, work,and in military or recreational activities. Iron deficiency at critical times of growth and development can result in premature births, low birth weight babies, delayed growth and development, delayed normal infant activity and movement. Which values are considered a low transferrin saturation in the blood?
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